It is not known to what degree, if any, topical hydroquinone is absorbed systemically. It is also not known whether hydroquinone can cause fetal harm when used topically on a pregnant woman or affect reproductive capacity. Pregnancy Category C: Animal reproduction studies have not been conducted with topical hydroquinone. PRECAUTIONS (ALSO SEE WARNINGS): Treatment should be limited to relatively small areas of the body at one time since some patients experience a transient skin reddening and a mild burning sensation, which does not preclude treatment. Sulfite sensitivity is seen more frequently in asthmatic than in nonasthmatic people. The overall prevalence of sulfite sensitivity in the general population is unknown and probably low. Sunscreen use is an essential aspect of hydroquinone therapy because even minimal sunlight exposure sustains melanocytic activity.Ĭontains sodium metabisulfite, a sulfite that may cause allergic-type reactions including anaphylactic symptoms and life-threatening or less severe asthmatic episodes in certain susceptible people. In case of accidental contact, patient should rinse eyes, nose, mouth, or lips with water and contact physician. Please see full Prescribing Information for Clear, Blender and SunfaderĪvoid contact with eyes, nose, mouth, or lips. The safety of topical hydroquinone use during pregnancy or in children (12 years and under) has not been established. Obagi Nu-Derm Clear, Blender and Sunfader (contains 4% hydroquinone)ĬONTRAINDICATIONS: People with prior history of sensitivity or allergic reaction to this product or any of its ingredients should not use it.
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